TACR2 (10q22.1) Substanssi K reseptori. Myös PI/Ca/G-proteiinisignalointiin assosioituva

 

Aliases for TACR2 Gene

• GeneCards Symbol: TACR2 ²
• Tachykinin Receptor 2 ^{2 3 4 5}
• NK2R ^{2 3 4 5}
• SKR ^{2 3 4 5}
• Neurokinin A Receptor ^{2 3 4}
• Substance-K Receptor ^{2 3 4}
• NKNAR ^{3 4 5}

• TAC2R ^{3 4 5}
• Neurokinin B Receptor ^{2 3}
• NK-2 Receptor ^{3 4}
• NK-2R ^{3 4}
• Seven Transmembrane Helix Receptor ³
• Neurokinin 2 Receptor ³

Entrez Gene Summary for TACR2 Gene

• This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A. [provided by RefSeq, Jul 2008]

GeneCards Summary for TACR2 Gene

TACR2 (Tachykinin Receptor 2) is a Protein Coding gene. Diseases associated with TACR2 include Baritosis and Constipation. Among its related pathways are RET signaling and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and substance K receptor activity. An important paralog of this gene is TACR3.

UniProtKB/Swiss-Prot Summary for TACR2 Gene

• This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.

  • NK2R_HUMAN,P21452

Tocris Summary for TACR2 Gene

• The neurokinin 2 (NK2) receptor is a member of the tachykinin family of G-protein-coupled receptors which also includes NK1 and NK3 receptors. The NK2 receptor is predominantly expressed in the periphery (including inflammatory cells and bronchial smooth muscle).

Gene Wiki entry for TACR2 Gene

Additional gene information for TACR2 Gene