PubMed haku: PIK3CD

Results: 1 to 20 of 68

1.

p110δ mutant mice reveal central role for PI3K signaling in intestinal macrophages.

Brown JB, Barrett TA.

Gastroenterology. 2010 Nov;139(5):1451-3. Epub 2010 Sep 25. No abstract available. PMID: 20875484 [PubMed - indexed for MEDLINE]Related citations

2.

Phosphoinositide 3-kinase δ regulates membrane fission of Golgi carriers for selective cytokine secretion.

Low PC, Misaki R, Schroder K, Stanley AC, Sweet MJ, Teasdale RD, Vanhaesebroeck B, Meunier FA, Taguchi T, Stow JL.

J Cell Biol. 2010 Sep 20;190(6):1053-65. Epub 2010 Sep 13.PMID: 20837769 [PubMed - indexed for MEDLINE]Related citations

3.

A novel MEK2/PI3Kδ pathway controls the expression of IL-1 receptor antagonist in IFN-β-activated human monocytes.

Brandt KJ, Carpintero R, Gruaz L, Molnarfi N, Burger D.

J Leukoc Biol. 2010 Dec;88(6):1191-200. Epub 2010 Sep 13.PMID: 20837746 [PubMed - indexed for MEDLINE]Related citations

4.

Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction.

Rolf J, Bell SE, Kovesdi D, Janas ML, Soond DR, Webb LM, Santinelli S, Saunders T, Hebeis B, Killeen N, Okkenhaug K, Turner M.

J Immunol. 2010 Oct 1;185(7):4042-52. Epub 2010 Sep 8.PMID: 20826752 [PubMed - indexed for MEDLINE]Related citations

5.

Phosphoinositide 3-kinase gamma mediates chemotactic responses of human eosinophils to platelet-activating factor.

Hasan AM, Mourtada-Maarabouni M, Hameed MS, Williams GT, Dent G.

Int Immunopharmacol. 2010 Sep;10(9):1017-21. Epub 2010 Jun 4.PMID: 20685403 [PubMed - indexed for MEDLINE]Related citations

6.

Activity of any class IA PI3K isoform can sustain cell proliferation and survival.

Foukas LC, Berenjeno IM, Gray A, Khwaja A, Vanhaesebroeck B.

Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11381-6. Epub 2010 Jun 7.PMID: 20534549 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

7.

Phosphatidylinositol 3-kinase-δ inhibitor CAL-101 shows promising preclinical activity in chronic lymphocytic leukemia by antagonizing intrinsic and extrinsic cellular survival signals.

Herman SE, Gordon AL, Wagner AJ, Heerema NA, Zhao W, Flynn JM, Jones J, Andritsos L, Puri KD, Lannutti BJ, Giese NA, Zhang X, Wei L, Byrd JC, Johnson AJ.

Blood. 2010 Sep 23;116(12):2078-88. Epub 2010 Jun 3.PMID: 20522708 [PubMed - indexed for MEDLINE]Related citations

8.

Type I interferon (IFN-alpha/beta) rescues B-lymphocytes from apoptosis via PI3Kdelta/Akt, Rho-A, NFkappaB and Bcl-2/Bcl(XL).

Badr G, Saad H, Waly H, Hassan K, Abdel-Tawab H, Alhazza IM, Ahmed EA.

Cell Immunol. 2010;263(1):31-40. Epub 2010 Feb 24.PMID: 20231019 [PubMed - indexed for MEDLINE]Related citations

9.

Pooled analysis of phosphatidylinositol 3-kinase pathway variants and risk of prostate cancer.

Koutros S, Schumacher FR, Hayes RB, Ma J, Huang WY, Albanes D, Canzian F, Chanock SJ, Crawford ED, Diver WR, Feigelson HS, Giovanucci E, Haiman CA, Henderson BE, Hunter DJ, Kaaks R, Kolonel LN, Kraft P, Le Marchand L, Riboli E, Siddiq A, Stampfer MJ, Stram DO, Thomas G, Travis RC, Thun MJ, Yeager M, Berndt SI.

Cancer Res. 2010 Mar 15;70(6):2389-96. Epub 2010 Mar 2.PMID: 20197460 [PubMed - indexed for MEDLINE]Related citations

10.

Discovery of dual inhibitors of the immune cell PI3Ks p110delta and p110gamma: a prototype for new anti-inflammatory drugs.

Williams O, Houseman BT, Kunkel EJ, Aizenstein B, Hoffman R, Knight ZA, Shokat KM.

Chem Biol. 2010 Feb 26;17(2):123-34.PMID: 20189103 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

11.

PI3K p110delta regulates T-cell cytokine production during primary and secondary immune responses in mice and humans.

Soond DR, Bjørgo E, Moltu K, Dale VQ, Patton DT, Torgersen KM, Galleway F, Twomey B, Clark J, Gaston JS, Taskén K, Bunyard P, Okkenhaug K.

Blood. 2010 Mar 18;115(11):2203-13. Epub 2010 Jan 15.PMID: 20081091 [PubMed - indexed for MEDLINE]Related citations

12.

PI3K isoforms as drug targets in inflammatory diseases: lessons from pharmacological and genetic strategies.

Harris SJ, Foster JG, Ward SG.

Curr Opin Investig Drugs. 2009 Nov;10(11):1151-62. Review.PMID: 19876783 [PubMed - indexed for MEDLINE]Related citations

13.

Phosphoinositide 3-kinase p110 delta regulates natural antibody production, marginal zone and B-1 B cell function, and autoantibody responses.

Durand CA, Hartvigsen K, Fogelstrand L, Kim S, Iritani S, Vanhaesebroeck B, Witztum JL, Puri KD, Gold MR.

J Immunol. 2009 Nov 1;183(9):5673-84.PMID: 19843950 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

14.

Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy.

Palazzolo I, Stack C, Kong L, Musaro A, Adachi H, Katsuno M, Sobue G, Taylor JP, Sumner CJ, Fischbeck KH, Pennuto M.

Neuron. 2009 Aug 13;63(3):316-28.PMID: 19679072 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

15.

RUNX1 regulates phosphoinositide 3-kinase/AKT pathway: role in chemotherapy sensitivity in acute megakaryocytic leukemia.

Edwards H, Xie C, LaFiura KM, Dombkowski AA, Buck SA, Boerner JL, Taub JW, Matherly LH, Ge Y.

Blood. 2009 Sep 24;114(13):2744-52. Epub 2009 Jul 28.PMID: 19638627 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

16.

Cell type specificity of PI3K signaling in Pdk1- and Pten-deficient brains.

Chalhoub N, Zhu G, Zhu X, Baker SJ.

Genes Dev. 2009 Jul 15;23(14):1619-24.PMID: 19605683 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

17.

Regulation of p110delta PI 3-kinase gene expression.

Kok K, Nock GE, Verrall EA, Mitchell MP, Hommes DW, Peppelenbosch MP, Vanhaesebroeck B.

PLoS One. 2009;4(4):e5145. Epub 2009 Apr 9.PMID: 19357769 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

18.

p110gamma and p110delta isoforms of phosphoinositide 3-kinase differentially regulate natural killer cell migration in health and disease.

Saudemont A, Garçon F, Yadi H, Roche-Molina M, Kim N, Segonds-Pichon A, Martín-Fontecha A, Okkenhaug K, Colucci F.

Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5795-800. Epub 2009 Mar 18.PMID: 19297623 [PubMed - indexed for MEDLINE]Free PMC ArticleFree textRelated citations

19.

Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice.

Marwick JA, Caramori G, Stevenson CS, Casolari P, Jazrawi E, Barnes PJ, Ito K, Adcock IM, Kirkham PA, Papi A.

Am J Respir Crit Care Med. 2009 Apr 1;179(7):542-8. Epub 2009 Jan 22.PMID: 19164702 [PubMed - indexed for MEDLINE]Free ArticleRelated citations

20.

Blockage by SP600125 of Fcepsilon receptor-induced degranulation and cytokine gene expression in mast cells is mediated through inhibition of phosphatidylinositol 3-kinase signalling pathway.

Tanemura S, Momose H, Shimizu N, Kitagawa D, Seo J, Yamasaki T, Nakagawa K, Kajiho H, Penninger JM, Katada T, Nishina H.

J Biochem. 2009 Mar;145(3):345-54. Epub 2008 Dec 23.PMID: 19106158 [PubMed - indexed for MEDLINE]Related citations