Kirjastokäynti. Kirjoja PI3K entsyymistä

Tänään havaitsin, että PI3K on oikein kirjana, kahtena volyymina.

Christian Rommel, Bart Vanhaesebroeck, Peter K.Vogt toimittivat kirjan nimeltä Phosphoinositide 3-kinase in Health and Disease .
Yläotsikkona aihepiirille Current Topics in Microbiology and Immunology.
Kirjan on kustantanut Springer Heidelberg Dordrecht London New York
Verlag: Springer Berlin Heidelberg 2010
ISBN: 978-3-642- 13663-4
Volyme 1

Ensimmäinen volyymi käsittelee seuraavat aihepiirit:
Johdanto
PDK1: The major transducer of PI3-Kinase acction
Protein Kinase B (PKB/Akt) a key mediator of the PI3K signaling pathways
PI3K in lymphocyte signaling and development
The regulation of class IA PI3 kinase by inter-subunit interactions
Phosphoinositide signalling pathways in metabolic regulation
Role of RAS in the regeneration of PI3-Kinase
More than just kinases: The scaffolding function of PI3K
PI3K signaling in neutrophils
PI3 kinase p110 beta regulation of platelet integrin alfa IIb beta3
Regulatory subunits of class IA PI3K
The neurodevelopmental implication of PI3K signaling
PI3K regulation of skeletal muscle hypertrophy and atrophy
Taking PI3K delta and PI3K gamma one step ahead: dual active PI3K delta/gamma inhibitors for the treatment of immuno-mediated inflammatory diseases.

Toinen volyymi on ISBN numeroltaan 978-3- 642-14814-6
Sen sisältö on seuraava:
PI3K: From the bench to the clinic and back
Oncogenic mutations of PI3KCA in human cancers
Structural effects of oncogenic PI3K mutations
Comparing the roles of the p110 beta isoforms of PI3K in signaling and cancer
Phosphatidylinositol 3-kinase: The oncoprotein
AKT signaling in physiology and disease
Faithful modeling of PTEN loss driven diseases in the mouse
PI3K as a target for therapy in haematological malignancies
Clinical development in phosphatidylinositol-3 kinase pathway inhibitors
From the bench to the bedside: PI3K pathwway inhibitors in clinical development
New inhibitorsof the PI3K-Akt-mTOR pathway: insights into mTOR signaling from a new generation of Tor kinase domain inhibitors
Small molecule inhibitors of the PI3-kinase family
Targeting the RTK-PI3K-mTOR axis in malignant disease: overcoming resistance

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