TACR3 geeni (4q24), Neuromediini-K- reseptori

 Tämä resettori TACR3  on Neurokiniini-3 reseptori tai  TACR3 tai neuromediini-K reseptori ja ligandina tälle on  prepro-takykiniini3 (geenistä TAC3)  koodautuva proteiini takykiniini-3 .(TAC3, 12q13.3. https://www.genecards.org/cgi-bin/carddisp.pl?gene=TAC3&keywords=ZNEUROK1

Entrez Gene Summary for TACR3 Gene

• This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B. [provided by RefSeq, Jul 2008]

GeneCards Summary for TACR3 Gene

TACR3 (Tachykinin Receptor 3) is a Protein Coding gene. Diseases associated with TACR3 include Hypogonadotropic Hypogonadism 11 With Or Without Anosmia and Kallmann Syndrome. Among its related pathways are RET signaling and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and tachykinin receptor activity. An important paralog of this gene is TACR1.

UniProtKB/Swiss-Prot Summary for TACR3 Gene

• This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.

  • NK3R_HUMAN,P29371

Tocris Summary for TACR3 Gene

• The neurokinin 3 (NK3) receptor is a member of the tachykinin family of G-protein-coupled receptors which also includes NK1 and NK2 receptors. The NK3 receptor is predominantly expressed in the CNS (including the hippocampus, hypothalamus and substantia nigra).

Gene Wiki entry for TACR3 Gene

Aliases for TACR3 Gene

• GeneCards Symbol: TACR3 ²
• Tachykinin Receptor 3 ^{2 3 4 5}
• TAC3R ^{2 3 4 5}
• NK3R ^{2 3 4 5}
• NKR ^{2 3 4 5}
• Neuromedin-K Receptor ^{2 3 4}
• Neurokinin B Receptor ^{2 3 4}

• Neurokinin Beta Receptor ^{2 3}
• NK-3 Receptor ^{3 4}
• NK3 Receptor ^{2 3}
• NK-3R ^{3 4}
• TAC3RL ³
• HH11 ³
• NK3 ³