IMPA, Inositolimonofosfataasi 1 (8q21.13)

 https://alphafold.ebi.ac.uk/entry/P29218

Protein

Inositol monophosphatase 1

Gene

IMPA1

Source organism

Homo sapiens (Human)go to search

UniProt

P29218go to UniProt

Experimental structures

13 structures in PDB for P29218go to PDBe-KB

Biological function

Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Has broad substrate specificity and can use myo-inositol monophosphates, myo-inositol 1,3-diphosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-phosphate, D-galactose 1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates.go to UniProt

• GeneCards Symbol: IMPA1 ²
• Inositol Monophosphatase 1 ^{2 3 4 5}
• IMPA ^{3 4 5}
• Lithium-Sensitive Myo-Inositol Monophosphatase A1 ^{3 4}
• Inositol(Myo)-1(Or 4)-Monophosphatase 1 ^{2 3}
• D-Galactose 1-Phosphate Phosphatase ^{3 4}
• Inositol-1(Or 4)-Monophosphatase 1 ^{3 4}
• Myo-Inositol Monophosphatase 1 ^{2 3}

• EC 3.1.3.25 ^{4 48}
• IMPase 1 ^{3 4}
• IMP 1 ^{3 4}
• Testicular Tissue Protein Li 94 ³
• EC 3.1.3.94 ⁴
• MRT59 ³
• IMP ³

External Ids for IMPA1 Gene