Annexiini A3, ANXA3 , pilkkoo syklisestä inositoli-1,2-fosfaatista esiin ins(1)fosfaattia

 

( 4q21.21) ANXA3 , Annexin A3

(inositoli-1,2- cykl.fosfaatti-2 fosfohydrolaasi)

https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/P12429

ANXA3

Organism:

Homo sapiens (Human)

Synonyms:

ANX3

Uniprot:

P12429go to UniProt

Biological function:

Inhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate go to UniProt

Aliases for ANXA3 Gene

https://www.genecards.org/cgi-bin/carddisp.plgene=ANXA3&keywords=ANXA3

• GeneCards Symbol: ANXA3

• Annexin A3

• ANX3

• Inositol 1,2-Cyclic Phosphate 2-Phosphohydrolase

• Placental Anticoagulant Protein III

• 35-Alpha Calcimedin

• Lipocortin III

• Annexin-3

• PAP-III

• Annexin III (Lipocortin III, 1,2-Cyclic-Inositol-Phosphate Phosphodiesterase, Placental Anticoagulant Protein III, Calcimedin 35-Alpha)

• Annexin III (Lipocortin III)

• Calcimedin 35-Alpha

• Annexin III

External Ids for ANXA3 Gene

Entrez Gene Summary for ANXA3 GeneThis gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq, Jul 2008]

GeneCards Summary for ANXA3 Gene

ANXA3 (Annexin A3) is a Protein Coding gene. Diseases associated with ANXA3 include Ovarian Cancer and Prostate Cancer. Among its related pathways are Prostaglandin synthesis and regulation. Gene Ontology (GO) annotations related to this gene include calcium ion binding and calcium-dependent phospholipid binding. An important paralog of this gene is ANXA4.

UniProtKB/Swiss-Prot Summary for ANXA3 Gene

Inhibitor of phospholipase A2, also possesses anti-coagulant properties. Also cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. ( ANXA3_HUMAN,P12429 )