NUDT19 (19q13.11) , mitchondrial , nucleoside diphosphate-linked moiety X motif 9

https://www.ncbi.nlm.nih.gov/gene/390916

Also known as

RP2

Expression

Ubiquitous expression in adrenal (RPKM 3.2), prostate (RPKM 2.7) and 25 other tissues See more

Orthologs

mouse all

Preferred Names

nucleoside diphosphate-linked moiety X motif 19

Names

CTC-379B2.4

nucleoside diphosphate-linked moiety X motif 19, mitochondrial

nudix (nucleoside diphosphate linked moiety X)-type motif 19

nudix motif 19

 

Structure, history

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LOCUS 

 XP_016882295             300 aa            linear   PRI 26-MAR-2018
DEFINITION 

 nucleoside diphosphate-linked moiety X motif 19 isoform X1 [Homo
            sapiens].
ACCESSION   XP_016882295
VERSION     XP_016882295.1
DBLINK      BioProject: PRJNA168
DBSOURCE    REFSEQ: accession XM_017026806.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT 

 MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000019.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Homo sapiens Annotation Release 109
            Annotation Version          :: 109
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="19"
     Protein         1..300
                     /product="nucleoside diphosphate-linked moiety X motif 19
                     isoform X1"
                     /calculated_mol_wt=32487
     CDS             1..300
                     /gene="NUDT19"
                     /gene_synonym="RP2"
                     /coded_by="XM_017026806.2:599..1501"
                     /db_xref="GeneID:390916"
                     /db_xref="HGNC:HGNC:32036"
ORIGIN      
        1 mssslrpgps rwrraasivl aagwsrpeta tppsrpppae gfrllllqrs phqgfmpgah
       61 vfsggvldaa drsadwlglf aphhgpprfg lgpapfsrta fpslpdtddh ktdntgtlpe
      121 dvafricavr eafeeagvll lrprtsppgp apgpglalep ppglaswrdr vrqdprhflr
      181 lcahldctpd iwalhnwsaw ltpflrgttr rfdtafflcc lrepppvypd laevvgyqnl
      241 qrsldpadrn scahqcssrn tscprtcnsp rtlligvvvl tnaaaettpa qepatvpgpc
//

Related articles in PubMed

1. Proteomic analysis of mouse kidney peroxisomes: identification of RP2p as a peroxisomal nudix hydrolase with acyl-CoA diphosphatase activity. Ofman R, et al. Biochem J, 2006 Jan 15. PMID 16185196, Free PMC Article
2. Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. GENDEP Investigators., et al. Am J Psychiatry, 2013 Feb. PMID 23377640
3. Seventy-five genetic loci influencing the human red blood cell. van der Harst P, et al. Nature, 2012 Dec 20. PMID 23222517, Free PMC Article
4. A proteome-wide perspective on peroxisome targeting signal 1(PTS1)-Pex5p affinities. Ghosh D, et al. J Am Chem Soc, 2010 Mar 24. PMID 20178365
5. Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function. Floyd BJ, et al. Mol Cell, 2016 Aug 18. PMID 27499296, Free PMC Article

See all (11) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

1. Observational study of gene-disease association. (HuGE Navigator)
2. Isolation and functional characterization of the NUDT19 ortholog in mouse.